What Are Examples Of Nephrotoxic Drugs?

Is aspirin a nephrotoxic drug?

Nonsteroidal anti-inflammatory medications (NSAIDs) are well known for nephrotoxicity, gastritis, and bleeding.

Aspirin, being a NSAID, can also potentially cause these complications.

Nephrotoxicity in the setting of kidney transplantation is even more important as the recipient only has one functional kidney..

What foods help repair kidneys?

A DaVita Dietitian’s Top 15 Healthy Foods for People with Kidney DiseaseRed bell peppers. 1/2 cup serving red bell pepper = 1 mg sodium, 88 mg potassium, 10 mg phosphorus. … Cabbage. 1/2 cup serving green cabbage = 6 mg sodium, 60 mg potassium, 9 mg phosphorus. … Cauliflower. … Garlic. … Onions. … Apples. … Cranberries. … Blueberries.More items…

What is the first sign of kidney problems?

Signs and symptoms of acute kidney failure may include: Decreased urine output, although occasionally urine output remains normal. Fluid retention, causing swelling in your legs, ankles or feet. Shortness of breath.

What four drugs have the potential to diminish renal?

Commonly-used drugs which can affect renal functionDiuretics.Beta blockers.Vasodilators.Non-steroidal anti-inflammatory drugs.ACE inhibitors.Aminoglycosides.Radio contrast media.Compound analgesics.More items…

What drugs can cause creatinine levels to rise?

Several drugs, such as cimetidine, trimethoprim, corticosteroids, pyrimethamine, phenacemide, salicylates and active vitamin D metabolites, have been reported to increase plasma creatinine without influencing its glomerular filtration.

What are the most common nephrotoxic drugs?

Drugs Associated with NephrotoxicityDrug class/drug(s)Pathophysiologic mechanism of renal injuryPhenytoin (Dilantin)Acute interstitial nephritisQuinine (Qualaquin)Thrombotic microangiopathyRanitidine (Zantac)Acute interstitial nephritisZoledronate (Zometa)Tubular cell toxicity52 more rows•Sep 15, 2008

What drugs are toxic to kidneys?

Medicines That Can Cause Acute Kidney InjuryAntibiotics. These include aminoglycosides, cephalosporins, amphotericin B, bacitracin, and vancomycin.Some blood pressure medicines. … Medicines used for cancer treatment (chemotherapy). … Dyes (contrast media). … Illegal drugs. … Medicines used to treat HIV. … Non-steroidal anti-inflammatory drugs. … Ulcer medicines.

What color is urine when your kidneys are failing?

When kidneys are failing, the increased concentration and accumulation of substances in urine lead to a darker color which may be brown, red or purple. The color change is due to abnormal protein or sugar, high levels of red and white blood cells, and high numbers of tube-shaped particles called cellular casts.

What is the most nephrotoxic antibiotic?

The potentially nephrotoxic antibiotics in current clinical use are neomycin, kanamycin, paromomycin, bacitracin, the polymyxins (polymyxin B, and colistin), and amphotericin B. Nephrotoxicity was reported with early lots of streptomycin, but the drug now commercially available does not appear to have this property.

Can kidneys repair themselves?

It was thought that kidney cells didn’t reproduce much once the organ was fully formed, but new research shows that the kidneys are regenerating and repairing themselves throughout life. Contrary to long-held beliefs, a new study shows that kidneys have the capacity to regenerate themselves.

Are bananas good for your kidneys?

Bananas are a rich source of potassium and may need to be limited on a renal diet. Pineapple is a kidney-friendly fruit, as it contains much less potassium than certain other tropical fruits.

Which antibiotic is not nephrotoxic?

Piperacillin-tazobactam, a penicillin antibiotic that is not commonly associated with nephrotoxicity, has more recently been associated with AKI when combined with vancomycin (13).

How is nephrotoxicity treated?

Chemotherapy drugs such as: Cisplatin, Carboplatin, Carmustine, Mitomycin, high-dose Methotrexate. Biologic therapy such as Interleukin-2, or Interferon Alfa. Antibiotics (such as Amphotericin B, Gentamycin and Vancomycin. Angiotensin-Converting Enzyme (ACE) Inhibitors – used in heart failure or after a heart attack.

What is toxic to kidneys?

Heavy Metals Cadmium, chromium, lead, mercury, platinum, and uranium are all nephrotoxic.